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A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp
The actions of Escherichia coli DNA Polymerase IV (Pol IV) in mutagenesis are managed by its interaction with the β sliding clamp. In the structure reported by Bunting et al. [EMBO J (2003) 22:5883–5892], the C-tail of Pol IV contacts a hydrophobic cleft on the clamp, while residues V303–P305 reach...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722325/ https://ncbi.nlm.nih.gov/pubmed/19617571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903460106 |
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