Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees

Persistent infection with hepatitis C virus (HCV) is among the leading causes of chronic liver disease. Previous studies suggested that genetic variation in hypervariable region 1 (HVR1) of the second envelope protein, possibly in response to host immune pressure, influences the outcome of HCV infec...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Forns, Xavier, Thimme, Robert, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., Chisari, Francis V., Bukh, Jens
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11078521/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230453597
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