Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees

Persistent infection with hepatitis C virus (HCV) is among the leading causes of chronic liver disease. Previous studies suggested that genetic variation in hypervariable region 1 (HVR1) of the second envelope protein, possibly in response to host immune pressure, influences the outcome of HCV infec...

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Autors principals: Forns, Xavier, Thimme, Robert, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., Chisari, Francis V., Bukh, Jens
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC27222/
https://ncbi.nlm.nih.gov/pubmed/11078521
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