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Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees

Persistent infection with hepatitis C virus (HCV) is among the leading causes of chronic liver disease. Previous studies suggested that genetic variation in hypervariable region 1 (HVR1) of the second envelope protein, possibly in response to host immune pressure, influences the outcome of HCV infec...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Forns, Xavier, Thimme, Robert, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., Chisari, Francis V., Bukh, Jens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11078521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230453597
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