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Regulation of vascular physiology and pathology by the S1P(2) receptor subtype
Sphingosine-1-phosphate (S1P) is now recognized as a lipid mediator that acts via G-protein-coupled receptors. S1P receptors couple to various heterotrimeric G-proteins and regulate downstream targets and ultimately cell behaviour. The prototypical S1P(1) receptor is known to couple to G(i) and regu...
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Format: | Artigo |
Jezik: | Inglês |
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Oxford University Press
2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721650/ https://ncbi.nlm.nih.gov/pubmed/19287048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp088 |
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