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Regulation of vascular physiology and pathology by the S1P(2) receptor subtype

Sphingosine-1-phosphate (S1P) is now recognized as a lipid mediator that acts via G-protein-coupled receptors. S1P receptors couple to various heterotrimeric G-proteins and regulate downstream targets and ultimately cell behaviour. The prototypical S1P(1) receptor is known to couple to G(i) and regu...

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Autori principali: Skoura, Athanasia, Hla, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721650/
https://ncbi.nlm.nih.gov/pubmed/19287048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp088
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