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Normal growth and development in mice over-expressing the CCN family member WISP3

Loss-of-function mutations in the gene WISP3 cause the autosomal recessive human skeletal disease Progressive Pseudorheumatoid Dysplasia, whereas mice with knockout mutations of Wisp3 have no phenotype. The lack of a phenotype in the Wisp3 knockout mice has constrained studies of the protein’s in vi...

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Detalhes bibliográficos
Main Authors: Nakamura, Yukio, Cui, Yajun, Fernando, Carol, Kutz, Wendy E., Warman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721080/
https://ncbi.nlm.nih.gov/pubmed/19401829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-009-0040-z
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