The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling

In humans, loss-of-function mutations in the gene encoding Wnt1 inducible signaling pathway protein 3 (WISP3) cause the autosomal-recessive skeletal disorder progressive pseudorheumatoid dysplasia (PPD). However, in mice there is no apparent phenotype caused by Wisp3 deficiency or overexpression. Co...

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Bibliografiset tiedot
Päätekijät: Nakamura, Yukio, Weidinger, Gilbert, Liang, Jennifer O., Aquilina-Beck, Allisan, Tamai, Keiko, Moon, Randall T., Warman, Matthew L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2007
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Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964511/
https://ncbi.nlm.nih.gov/pubmed/17823661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32001
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