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Quantitation of Aurora Kinase A Gene Copy Number in Urine Sediments and Bladder Cancer Detection

BACKGROUND: Chromosome missegregation and the resulting aneuploidy is a common change in neoplasia. The Aurora kinase A (AURKA) gene, which encodes a key regulator of mitosis, is frequently amplified and/or overexpressed in cancer cells, and the level of AURKA amplification is associated with the le...

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Detalhes bibliográficos
Main Authors: Park, Hong-Seok, Park, Weon Seo, Bondaruk, Jolanta, Tanaka, Noriyoshi, Katayama, Hiroshi, Lee, Sangkyou, Spiess, Philippe E., Steinberg, Jordan R., Wang, Zhi, Katz, Ruth L., Dinney, Colin, Elias, Keren J., Lotan, Yair, Naeem, Rizwan C., Baggerly, Keith, Sen, Subrata, Grossman, H. Barton, Czerniak, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720731/
https://ncbi.nlm.nih.gov/pubmed/18812553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn304
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