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Quantitation of Aurora Kinase A Gene Copy Number in Urine Sediments and Bladder Cancer Detection
BACKGROUND: Chromosome missegregation and the resulting aneuploidy is a common change in neoplasia. The Aurora kinase A (AURKA) gene, which encodes a key regulator of mitosis, is frequently amplified and/or overexpressed in cancer cells, and the level of AURKA amplification is associated with the le...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720731/ https://ncbi.nlm.nih.gov/pubmed/18812553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn304 |
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