Quantitation of Aurora Kinase A Gene Copy Number in Urine Sediments and Bladder Cancer Detection

BACKGROUND: Chromosome missegregation and the resulting aneuploidy is a common change in neoplasia. The Aurora kinase A (AURKA) gene, which encodes a key regulator of mitosis, is frequently amplified and/or overexpressed in cancer cells, and the level of AURKA amplification is associated with the le...

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Hlavní autoři: Park, Hong-Seok, Park, Weon Seo, Bondaruk, Jolanta, Tanaka, Noriyoshi, Katayama, Hiroshi, Lee, Sangkyou, Spiess, Philippe E., Steinberg, Jordan R., Wang, Zhi, Katz, Ruth L., Dinney, Colin, Elias, Keren J., Lotan, Yair, Naeem, Rizwan C., Baggerly, Keith, Sen, Subrata, Grossman, H. Barton, Czerniak, Bogdan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720731/
https://ncbi.nlm.nih.gov/pubmed/18812553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn304
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