Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior

The effects of AURKA overexpression associated with poor clinical outcomes have been attributed to increased cell cycle progression and the development of genomic instability with aneuploidy. We used RNA interference to examine the effects of AURKA overexpression in human bladder cancer cells. Knock...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mobley, Aaron, Zhang, Shizhen, Bondaruk, Jolanta, Wang, Yan, Majewski, Tadeusz, Caraway, Nancy P., Huang, Li, Shoshan, Einav, Velazquez-Torres, Guermarie, Nitti, Giovanni, Lee, Sangkyou, Lee, June Goo, Fuentes-Mattei, Enrique, Willis, Daniel, Zhang, Li, Guo, Charles C., Yao, Hui, Baggerly, Keith, Lotan, Yair, Lerner, Seth P., Dinney, Colin, McConkey, David, Bar-Eli, Menashe, Czerniak, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244380/
https://ncbi.nlm.nih.gov/pubmed/28102366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40714
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