Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior

The effects of AURKA overexpression associated with poor clinical outcomes have been attributed to increased cell cycle progression and the development of genomic instability with aneuploidy. We used RNA interference to examine the effects of AURKA overexpression in human bladder cancer cells. Knock...

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Vydáno v:Sci Rep
Hlavní autoři: Mobley, Aaron, Zhang, Shizhen, Bondaruk, Jolanta, Wang, Yan, Majewski, Tadeusz, Caraway, Nancy P., Huang, Li, Shoshan, Einav, Velazquez-Torres, Guermarie, Nitti, Giovanni, Lee, Sangkyou, Lee, June Goo, Fuentes-Mattei, Enrique, Willis, Daniel, Zhang, Li, Guo, Charles C., Yao, Hui, Baggerly, Keith, Lotan, Yair, Lerner, Seth P., Dinney, Colin, McConkey, David, Bar-Eli, Menashe, Czerniak, Bogdan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244380/
https://ncbi.nlm.nih.gov/pubmed/28102366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40714
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