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Active site gating regulates substrate selectivity in a chymotrypsin-like serine protease. The structure of Haemophilus influenzae IgA1 protease
We report here the first structure of a member of the IgA protease family at 1.75Å resolution. This protease is a founding member of the Type V (autotransporter) secretion system and is considered a virulence determinant among the bacteria expressing the enzyme. The structure of the enzyme fits that...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720633/ https://ncbi.nlm.nih.gov/pubmed/19393662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.041 |
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