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Microbial IgA Protease Removes IgA Immune Complexes from Mouse Glomeruli In Vivo: Potential Therapy for IgA Nephropathy

The hallmark of IgA nephropathy (IgAN), the most common form of glomerulonephritis, is the presence of mesangial deposits containing IgA, specifically the IgA1 subclass, as the most prominent component. The deposited IgA is considered to be part of an immune complex. The family of enzymes known as b...

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Autori principali: Lamm, Michael E., Emancipator, Steven N., Robinson, Janet K., Yamashita, Michifumi, Fujioka, Hisashi, Qiu, Jiazhou, Plaut, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189629/
https://ncbi.nlm.nih.gov/pubmed/18165266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070131
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