Caricamento...

POTENT INHIBITION OF HUMAN AP ENDONUCLEASE 1 BY ARYLSTIBONIC ACIDS

Human apurinic/apyrimidinic endonuclease (Ape1) plays an important role by processing the >10,000 highly toxic abasic sites generated in the genome of each cell every day. Ape1 has recently emerged as a target for inhibition as its overexpression in tumors has been linked with poor response to bo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Seiple, Lauren A., Cardellina, John H., Akee, Rhone, Stivers, James T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720577/
https://ncbi.nlm.nih.gov/pubmed/18042731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.042622
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !