Mice with a targeted mutation in the thyroid hormone β receptor gene exhibit impaired growth and resistance to thyroid hormone

Patients with mutations in the thyroid hormone receptor β (TRβ) gene manifest resistance to thyroid hormone (RTH), resulting in a constellation of variable phenotypic abnormalities. To understand the molecular basis underlying the action of mutant TRβ in vivo, we generated mice with a targeted mutat...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Kaneshige, Masahiro, Kaneshige, Kumiko, Zhu, Xu-guang, Dace, Alexandra, Garrett, Lisa, Carter, Todd A., Kazlauskaite, Rasa, Pankratz, Daniel G., Wynshaw-Boris, Anthony, Refetoff, Samuel, Weintraub, Bruce, Willingham, Mark C., Barlow, Carrolee, Cheng, Sheue-yann
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2000
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27204/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11069286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230285997
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!