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Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage–reunion domain of Escherichia coli DNA gyrase

Crystals of a complex formed between the 59 kDa N-terminal fragment of the Escherichia coli DNA gyrase A subunit (also known as the breakage–reunion domain) and the antibiotic simocyclinone D8 were grown by vapour diffusion. The complex crystallized with I-centred orthorhombic symmetry and X-ray dat...

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Detalhes bibliográficos
Main Authors: Edwards, Marcus J., Flatman, Ruth H., Mitchenall, Lesley A., Stevenson, Clare E. M., Maxwell, Anthony, Lawson, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720350/
https://ncbi.nlm.nih.gov/pubmed/19652356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109028097
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