Structure-Activity Relationships of Aminocoumarin-Type Gyrase and Topoisomerase IV Inhibitors Obtained by Combinatorial Biosynthesis

Por Flatman, Ruth H., Eustaquio, Alessandra, Li, Shu-Ming, Heide, Lutz, Maxwell, Anthony
Publicado em 2006

Simocyclinone D8, an Inhibitor of DNA Gyrase with a Novel Mode of Action

Por Flatman, Ruth H., Howells, Alison J., Heide, Lutz, Fiedler, Hans-Peter, Maxwell, Anthony
Publicado em 2005

Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage–reunion domain of Escherichia coli DNA gyrase

Por Edwards, Marcus J., Flatman, Ruth H., Mitchenall, Lesley A., Stevenson, Clare E. M., Maxwell, Anthony, Lawson, David M.
Publicado em 2009