Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array

PURPOSE: To identify new polymorphisms (single nucleotide polymorphisms, SNPs) in DNA repair pathways that are associated with efficacy and toxicity in patients receiving oxaliplatin and capecitabine for advanced colorectal cancer (ACC). METHODS: We studied progression-free survival (PFS) in 91 ACC...

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Detaylı Bibliyografya
Asıl Yazarlar: Kweekel, D M, Antonini, N F, Nortier, J W R, Punt, C J A, Gelderblom, H, Guchelaar, H-J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Genetics and Genomics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720215/
https://ncbi.nlm.nih.gov/pubmed/19536092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605134
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