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High-resolution analysis of epigenetic changes associated with X inactivation

Differentiation of female murine ES cells triggers silencing of one X chromosome through X-chromosome inactivation (XCI). Immunofluorescence studies showed that soon after Xist RNA coating the inactive X (Xi) undergoes many heterochromatic changes, including the acquisition of H3K27me3. However, the...

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Autors principals: Marks, Hendrik, Chow, Jennifer C., Denissov, Sergei, Françoijs, Kees-Jan, Brockdorff, Neil, Heard, Edith, Stunnenberg, Hendrik G.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720191/
https://ncbi.nlm.nih.gov/pubmed/19581487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.092643.109
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