A role for cFLIP in B cell proliferation and stress MAP kinase regulation

Fas/Apo-1 signals through the FADD adaptor protein which recruits and activates the apical Caspase 8, and leads to apoptosis. cFLIP is a homologue of Caspase 8 and also capable of binding to FADD. Previous studies suggest that cFLIP could either enhance or inhibit apoptosis, and lead to NF-κB and Er...

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Main Authors: Zhang, Haibing, Rosenberg, Stephen, Coffey, Francis J., He, You-Wen, Manser, Timothy, Hardy, Richard R., Zhang, Jianke
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720129/
https://ncbi.nlm.nih.gov/pubmed/19109151
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