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EARLY AND LATE CONTRIBUTIONS OF GLUTAMATE AND CGRP TO MECHANICAL SENSITIZATION BY ENDOTHELIN-1

Intraplantar injection of endothelin-1 (ET-1) (1.5-10 μM) in the rat produces mechanical allodynia. Here we identify the receptor subtypes for ET-1, glutamate and CGRP critical to such allodynia. Antagonism of ET(A) or ET(B) receptors alone, by BQ123 or BQ788, respectively, only partially suppressed...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Khodorova, Alla, Richter, Judith, Vasko, Michael R., Strichartz, Gary
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720062/
https://ncbi.nlm.nih.gov/pubmed/19559390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2009.01.265
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