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Selective Raf Inhibition in Cancer Therapy

Over the past 5 years, the Raf kinase family has emerged as a promising target for protein-directed cancer therapy development. The goal of this review is to first provide a concise summary of the data validating Raf proteins as high-interest therapeutic targets. We then outline the mode of action o...

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Autori principali: Khazak, Vladimir, Astsaturov, Igor, Serebriiskii, Ilya G, Golemis, Erica A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720036/
https://ncbi.nlm.nih.gov/pubmed/18020980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.11.12.1587
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