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Possible role for interactions between 5-lipoxygenase (5-LOX) and AMPA GluR1 receptors in depression and in antidepressant therapy
Emerging evidence suggests that 5-lipoxygenase (5-LOX) plays a role in central nervous system functioning. It has been shown that 5-LOX metabolic products can decrease the phosphorylation of the glutamate reseptor subunit GluR1, and that this effect can be antagonized by 5-LOX inhibitors. Recent con...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719960/ https://ncbi.nlm.nih.gov/pubmed/17449191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2007.02.038 |
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