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Effects of Minocycline on Cocaine Sensitization and Phosphorylation of GluR1 Receptors in 5-Lipoxygenase Deficient Mice

In wild-type (WT) mice, the antibiotic minocycline inhibits development of cocaine-induced locomotor sensitization. Some of the actions of minocycline may involve the 5-lipoxygenase (5-LOX) pathway. We used the model of 5-LOX-deficient mice to investigate whether 5-LOX participates in minocycline’s...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Hu, Manev, Hari
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019259/
https://ncbi.nlm.nih.gov/pubmed/20868701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.09.006
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