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Engaging the lysosomal compartment to combat B cell malignancies
The combination of rituximab, a type I anti-CD20 mAb, with conventional chemotherapy has significantly improved the outcome of patients with B cell malignancies. Regardless of this success, many patients still relapse with therapy-resistant disease, highlighting the need for the development of mAbs...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719949/ https://ncbi.nlm.nih.gov/pubmed/19620776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40259 |
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