A new immunodeficient hyperglycaemic mouse model based on the Ins2(Akita) mutation for analyses of human islet and beta stem and progenitor cell function

AIMS/HYPOTHESIS: To develop and validate a new immuno-deficient mouse strain that spontaneously develops a non-autoimmune hyperglycaemia to serve as a diabetic host for human islets and human beta stem and progenitor cells without the need for induction of hyperglycaemia by toxic chemicals with thei...

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Main Authors: Pearson, T., Shultz, L. D., Lief, J., Burzenski, L., Gott, B., Chase, T., Foreman, O., Rossini, A. A., Bottino, R., Trucco, M., Greiner, D. L.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719841/
https://ncbi.nlm.nih.gov/pubmed/18563383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1057-1
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