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A new immunodeficient hyperglycaemic mouse model based on the Ins2(Akita) mutation for analyses of human islet and beta stem and progenitor cell function
AIMS/HYPOTHESIS: To develop and validate a new immuno-deficient mouse strain that spontaneously develops a non-autoimmune hyperglycaemia to serve as a diabetic host for human islets and human beta stem and progenitor cells without the need for induction of hyperglycaemia by toxic chemicals with thei...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2008
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719841/ https://ncbi.nlm.nih.gov/pubmed/18563383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1057-1 |
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