The Exosome Associates Cotranscriptionally with the Nascent Pre-mRNP through Interactions with Heterogeneous Nuclear Ribonucleoproteins

Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be deleterious for the cell. The exosome, a protein complex with ribonuclease activity, is a key player in quality control. An early quality checkpoi...

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Hlavní autoři: Hessle, Viktoria, Björk, Petra, Sokolowski, Marcus, de Valdivia, Ernesto González, Silverstein, Rebecca, Artemenko, Konstantin, Tyagi, Anu, Maddalo, Gianluca, Ilag, Leopold, Helbig, Roger, Zubarev, Roman A., Visa, Neus
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719564/
https://ncbi.nlm.nih.gov/pubmed/19494042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0079
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