The Exosome Associates Cotranscriptionally with the Nascent Pre-mRNP through Interactions with Heterogeneous Nuclear Ribonucleoproteins

Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be deleterious for the cell. The exosome, a protein complex with ribonuclease activity, is a key player in quality control. An early quality checkpoi...

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Detalhes bibliográficos
Main Authors: Hessle, Viktoria, Björk, Petra, Sokolowski, Marcus, de Valdivia, Ernesto González, Silverstein, Rebecca, Artemenko, Konstantin, Tyagi, Anu, Maddalo, Gianluca, Ilag, Leopold, Helbig, Roger, Zubarev, Roman A., Visa, Neus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719564/
https://ncbi.nlm.nih.gov/pubmed/19494042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0079
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