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The Exosome Associates Cotranscriptionally with the Nascent Pre-mRNP through Interactions with Heterogeneous Nuclear Ribonucleoproteins

Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be deleterious for the cell. The exosome, a protein complex with ribonuclease activity, is a key player in quality control. An early quality checkpoi...

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Bibliografiske detaljer
Main Authors: Hessle, Viktoria, Björk, Petra, Sokolowski, Marcus, de Valdivia, Ernesto González, Silverstein, Rebecca, Artemenko, Konstantin, Tyagi, Anu, Maddalo, Gianluca, Ilag, Leopold, Helbig, Roger, Zubarev, Roman A., Visa, Neus
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719564/
https://ncbi.nlm.nih.gov/pubmed/19494042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0079
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