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Short protein segments can drive a non-fibrillizing protein into the amyloid state

Protein fibrils termed amyloid-like are associated with numerous degenerative diseases as well as some normal cellular functions. Specific short segments of amyloid-forming proteins have been shown to form fibrils themselves. However, it has not been shown in general that these segments are capable...

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Detalhes bibliográficos
Main Authors: Teng, Poh K., Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719503/
https://ncbi.nlm.nih.gov/pubmed/19602569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp037
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