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Mitochondrial Targeting of Cytochrome P450 Proteins Containing NH(2)-terminal Chimeric Signals Involves an Unusual TOM20/TOM22 Bypass Mechanism

Previously we showed that xenobiotic inducible cytochrome P450 (CYP) proteins are bimodally targeted to the endoplasmic reticulum and mitochondria. In this study, we investigated the mechanism of delivery of chimeric signal containing CYP proteins to the peripheral and channel-forming mitochondrial...

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Auteurs principaux: Anandatheerthavarada, Hindupur K., Sepuri, Naresh Babu V., Avadhani, Narayan G.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719370/
https://ncbi.nlm.nih.gov/pubmed/19401463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007492
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