Unique Ligand Selectivity of the GPR92/LPA(5) Lysophosphatidate Receptor Indicates Role in Human Platelet Activation

Lysophosphatidic acid (LPA) is a ligand for LPA(1–3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4–8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship (SAR) of GPR92/LPA(5) is limited and whether LPA i...

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Autori principali: Williams, Jesica R., Khandoga, Anna L., Goyal, Pankaj, Fells, James I., Perygin, Donna H., Siess, Wolfgang, Parrill, Abby L., Tigyi, Gabor, Fujiwara, Yuko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719366/
https://ncbi.nlm.nih.gov/pubmed/19366702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003194
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