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The Antifungal Agent Itraconazole Induces the Accumulation of High Mannose Glycoproteins in Macrophages

Bacterial lipopolysaccharide (LPS) is a key mediator in the development of Gram-negative septic shock, which is a major health problem. The effect of LPS on myeloid cells is mediated by a multicomplex receptor system in which CD14, a glycosylphosphatidylinositol-anchored glycoprotein, and Toll-like...

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Библиографические подробности
Главные авторы: Frey, Tiffany, De Maio, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719324/
https://ncbi.nlm.nih.gov/pubmed/19414590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007609
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