Dual Functions for LTBP in Lung Development: LTBP-4 Independently Modulates Elastogenesis and TGF-β Activity

The latent TGF-β binding proteins (LTBP) −1, −3, and −4 are extracellular proteins that assist in the secretion and localization of latent TGF-β. The null mutation of LTBP-4S in mice causes defects in the differentiation of terminal air-sacs, fragmented elastin, and colon carcinomas. We investigated...

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Bibliografiske detaljer
Main Authors: Dabovic, Branka, Chen, Yan, Choi, Jiwon, Vassallo, Melinda, Dietz, Harry C., Ramirez, Francesco, von Melchner, Harald, Davis, Elaine C., Rifkin, Daniel B.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719250/
https://ncbi.nlm.nih.gov/pubmed/19016471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21643
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