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Runx2 Recruits p300 to Mediate Parathyroid Hormone’s Effects on Histone Acetylation and Transcriptional Activation of the Matrix Metalloproteinase-13 Gene

PTH regulates transcription of a number of genes involved in bone remodeling and calcium homeostasis. We have previously shown that the matrix metalloproteinase-13 (MMP-13) gene is induced by PTH in osteoblastic cells as a secondary response through the protein kinase A pathway requiring the runt do...

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Bibliographische Detailangaben
Hauptverfasser: Boumah, Christine E., Lee, Minnkyong, Selvamurugan, Nagarajan, Shimizu, Emi, Partridge, Nicola C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718752/
https://ncbi.nlm.nih.gov/pubmed/19423655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0217
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