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Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences

Motivation: The identification of transcription factor (TF) binding sites and the regulatory circuitry that they define is currently an area of intense research. Data from whole-genome chromatin immunoprecipitation (ChIP–chip), whole-genome expression microarrays, and sequencing of multiple closely...

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Hlavní autoři: Ward, Lucas D., Bussemaker, Harmen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718632/
https://ncbi.nlm.nih.gov/pubmed/18586710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn154
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