Regulation of apoptosis at cell division by p34(cdc2) phosphorylation of survivin

The interface between apoptosis (programmed cell death) and the cell cycle is essential to preserve homeostasis and genomic integrity. Here, we show that survivin, an inhibitor of apoptosis over-expressed in cancer, physically associates with the cyclin-dependent kinase p34(cdc2) on the mitotic appa...

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Main Authors: O'Connor, Daniel S., Grossman, Douglas, Plescia, Janet, Li, Fengzhi, Zhang, Hui, Villa, Antonello, Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC27185/
https://ncbi.nlm.nih.gov/pubmed/11069302
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