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Closing gaps in the human genome using sequencing by synthesis

The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class of gaps is likely to be refractory to clone-based approaches, and...

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Dettagli Bibliografici
Autori principali: Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, Lennon, Niall, Nusbaum, Chad
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718494/
https://ncbi.nlm.nih.gov/pubmed/19490611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-6-r60
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