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Closing gaps in the human genome using sequencing by synthesis

The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class of gaps is likely to be refractory to clone-based approaches, and...

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Main Authors: Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, Lennon, Niall, Nusbaum, Chad
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718494/
https://ncbi.nlm.nih.gov/pubmed/19490611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-6-r60
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