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Closing Human Reference Genome Gaps: Identifying and Characterizing Gap-Closing Sequences

Despite continuous updates of the human reference genome, there are still hundreds of unresolved gaps which account for about 5% of the total sequence length. Given the availability of whole genome de novo assemblies, especially those derived from long-read sequencing data, gap-closing sequences can...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Zhao, Tingting, Duan, Zhongqu, Genchev, Georgi Z., Lu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407462/
https://ncbi.nlm.nih.gov/pubmed/32532800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401280
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