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Inducible Nitric Oxide Synthase in Long-term Intermittent Hypoxia: Hypersomnolence and Brain Injury

Rationale: Long-term intermittent hypoxia (LTIH) exposure in adult mice, modeling oxygenation patterns of moderate–severe obstructive sleep apnea, results in lasting hypersomnolence and is associated with nitration and oxidation injuries in many brain regions, including wake-active regions. Objectiv...

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Detalhes bibliográficos
Main Authors: Zhan, Guanxia, Fenik, Polina, Pratico, Domenico, Veasey, Sigrid C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718483/
https://ncbi.nlm.nih.gov/pubmed/15750040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200411-1564OC
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