NADPH Oxidase Mediates Hypersomnolence and Brain Oxidative Injury in a Murine Model of Sleep Apnea

Rationale: Persons with obstructive sleep apnea may have significant residual hypersomnolence, despite therapy. Long-term hypoxia/reoxygenation events in adult mice, simulating oxygenation patterns of moderate–severe sleep apnea, result in lasting hypersomnolence, oxidative injury, and proinflammato...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhan, Guanxia, Serrano, Faridis, Fenik, Polina, Hsu, Ray, Kong, Linghao, Pratico, Domenico, Klann, Eric, Veasey, Sigrid C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2005
Schlagworte:
F. Sleep and Control of Ventilation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718406/
https://ncbi.nlm.nih.gov/pubmed/15994465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200504-581OC
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