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Chronic Intermittent Hypoxia Alters Density of Aminergic Terminals and Receptors in the Hypoglossal Motor Nucleus

Rationale: Patients with obstructive sleep apnea (OSA) adapt to the anatomical vulnerability of their upper airway by generating increased activity in upper airway–dilating muscles during wakefulness. Norepinephrine (NE) and serotonin (5-HT) mediate, through α(1)-adrenergic and 5-HT(2A) receptors, a...

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Autores principales: Rukhadze, Irma, Fenik, Victor B., Benincasa, Kate E., Price, Andrea, Kubin, Leszek
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001268/
https://ncbi.nlm.nih.gov/pubmed/20622040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200912-1884OC
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