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Adhesive Dynamics Simulation of G-Protein-Mediated Chemokine-Activated Neutrophil Adhesion

To reach sites of inflammation, a blood-borne neutrophil first rolls over the vessel wall, becoming firmly adherent on activation, and then transmigrates through the endothelium. In this study, we simulate the transition to firm adhesion via chemokine-induced integrin activation. To recreate the tra...

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Détails bibliographiques
Auteurs principaux: Caputo, Kelly E., Hammer, Daniel A.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718305/
https://ncbi.nlm.nih.gov/pubmed/19383446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3930
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