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Adhesive Dynamics Simulation of G-Protein-Mediated Chemokine-Activated Neutrophil Adhesion

To reach sites of inflammation, a blood-borne neutrophil first rolls over the vessel wall, becoming firmly adherent on activation, and then transmigrates through the endothelium. In this study, we simulate the transition to firm adhesion via chemokine-induced integrin activation. To recreate the tra...

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Autors principals: Caputo, Kelly E., Hammer, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718305/
https://ncbi.nlm.nih.gov/pubmed/19383446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3930
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