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Effect of Microvillus Deformability on Leukocyte Adhesion Explored Using Adhesive Dynamics Simulations

Leukocyte rolling on the endothelium via selectin molecules is an important step in the adhesion cascade, which allows leukocytes in the bloodstream to reach sites of infection. We improve upon Adhesive Dynamics simulations by incorporating deformable microvilli on which adhesion molecules are clust...

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Bibliografiske detaljer
Main Authors: Caputo, Kelly E., Hammer, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366517/
https://ncbi.nlm.nih.gov/pubmed/15879471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.054171
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