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Effect of Microvillus Deformability on Leukocyte Adhesion Explored Using Adhesive Dynamics Simulations

Leukocyte rolling on the endothelium via selectin molecules is an important step in the adhesion cascade, which allows leukocytes in the bloodstream to reach sites of infection. We improve upon Adhesive Dynamics simulations by incorporating deformable microvilli on which adhesion molecules are clust...

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Autors principals: Caputo, Kelly E., Hammer, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366517/
https://ncbi.nlm.nih.gov/pubmed/15879471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.054171
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