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Brownian Adhesive Dynamics (BRAD) for Simulating the Receptor-Mediated Binding of Viruses

Current viral docking models have relied upon the assumption that bond formation and breakage are independent of viral and docking surface geometry, as well as the forces exerted on the bonds. This assumption, known as the equivalent site hypothesis (ESH), is examined in detail using a newly develop...

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Bibliografiske detaljer
Main Authors: English, Thomas J., Hammer, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304245/
https://ncbi.nlm.nih.gov/pubmed/15189840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.027813
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