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Brownian Adhesive Dynamics (BRAD) for Simulating the Receptor-Mediated Binding of Viruses

Current viral docking models have relied upon the assumption that bond formation and breakage are independent of viral and docking surface geometry, as well as the forces exerted on the bonds. This assumption, known as the equivalent site hypothesis (ESH), is examined in detail using a newly develop...

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Detalhes bibliográficos
Main Authors: English, Thomas J., Hammer, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304245/
https://ncbi.nlm.nih.gov/pubmed/15189840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.027813
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