Structure and function of a complex between chorismate mutase and DAHP synthase: efficiency boost for the junior partner

Chorismate mutase catalyzes a key step in the shikimate biosynthetic pathway towards phenylalanine and tyrosine. Curiously, the intracellular chorismate mutase of Mycobacterium tuberculosis (MtCM; Rv0948c) has poor activity and lacks prominent active-site residues. However, its catalytic efficiency...

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Bibliographische Detailangaben
Hauptverfasser: Sasso, Severin, Ökvist, Mats, Roderer, Kathrin, Gamper, Marianne, Codoni, Giosiana, Krengel, Ute, Kast, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718287/
https://ncbi.nlm.nih.gov/pubmed/19556970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.165
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