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Paraoxonase 1 (PON1) Modulates the Toxicity of Mixed Organophosphorus Compounds
A transgenic mouse model of the human hPON1(Q192R) polymorphism was used to address the role of paraoxonase (PON1) in modulating toxicity associated with exposure to mixtures of organophosphorus (OP) compounds. Chlorpyrifos oxon (CPO), diazoxon (DZO), and paraoxon (PO) are potent inhibitors of carbo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717945/ https://ncbi.nlm.nih.gov/pubmed/19371602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.02.001 |
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