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The Toxicity of Mixtures of Specific Organophosphorus Compounds is Modulated by Paraoxonase 1 Status

Most chemical exposures involve complex mixtures. The role of paraoxonase 1 (PON1) and the Q192R polymorphism in the detoxication of individual organophosphorous (OP) compounds has been well-established. The extent to which PON1 protects against a given OP is determined by its catalytic efficiency....

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Detalhes bibliográficos
Main Authors: Cole, Toby B., Jansen, Karen, Park, Sarah, Li, Wan-Fen, Furlong, Clement E., Costa, Lucio G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035621/
https://ncbi.nlm.nih.gov/pubmed/20221870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-350-3_6
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