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The Toxicity of Mixtures of Specific Organophosphorus Compounds is Modulated by Paraoxonase 1 Status
Most chemical exposures involve complex mixtures. The role of paraoxonase 1 (PON1) and the Q192R polymorphism in the detoxication of individual organophosphorous (OP) compounds has been well-established. The extent to which PON1 protects against a given OP is determined by its catalytic efficiency....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035621/ https://ncbi.nlm.nih.gov/pubmed/20221870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-350-3_6 |
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