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Repeated Developmental Exposure of Mice to Chlorpyrifos Oxon Is Associated with Paraoxonase 1 (PON1)-Modulated Effects on Cerebellar Gene Expression

Microarray analysis was used to examine effects of repeated postnatal exposure to chlorpyrifos oxon (CPO) on gene expression in the cerebellum of genetically modified mice. The high-density lipoprotein-associated enzyme paraoxonase 1 (PON1) plays a significant role in the detoxication of CPO, which...

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Detalhes bibliográficos
Main Authors: Cole, Toby B., Beyer, Richard P., Bammler, Theo K., Park, Sarah S., Farin, Federico M., Costa, Lucio G., Furlong, Clement E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164442/
https://ncbi.nlm.nih.gov/pubmed/21673326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr157
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