Blood-Brain Barrier Disruption and Intra-Arterial Methotrexate-Based Therapy for Newly Diagnosed Primary CNS Lymphoma: A Multi-Institutional Experience

PURPOSE: Primary CNS lymphoma (PCNSL) is confined to the CNS and/or the eyes at presentation and is usually initially treated with intravenous methotrexate-based chemotherapy and whole-brain radiotherapy (WBRT). However, the intact blood-brain barrier (BBB) can limit diffusion of methotrexate into b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Angelov, Lilyana, Doolittle, Nancy D., Kraemer, Dale F., Siegal, Tali, Barnett, Gene H., Peereboom, David M., Stevens, Glen, McGregor, John, Jahnke, Kristoph, Lacy, Cynthia A., Hedrick, Nancy A., Shalom, Edna, Ference, Sandra, Bell, Susan, Sorenson, Lisa, Tyson, Rose Marie, Haluska, Marianne, Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717756/
https://ncbi.nlm.nih.gov/pubmed/19451444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.3789
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados