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Serum DNA can define tumor-specific genetic and epigenetic markers in gliomas of various grades

We evaluated whether cell-free circulating DNA can be used as a noninvasive approach for detection of genetic/epigenetic alterations in brain tumors during the course of the disease. Paired tumor-serum samples from 70 patients with either high-grade astrocytomas (n = 41) or oligodendrogliomas of var...

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Detalhes bibliográficos
Main Authors: Lavon, Iris, Refael, Miri, Zelikovitch, Bracha, Shalom, Edna, Siegal, Tali
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940579/
https://ncbi.nlm.nih.gov/pubmed/20150384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop041
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